Descemet Stripping Endothelial Keratoplasty (DSEK/DSAEK)
Descemet Stripping Endothelial Keratoplasty (DSEK), also known as Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), is a modern type of corneal transplant surgery used to treat problems affecting the inner endothelial layer of the cornea. Unlike a full-thickness corneal transplant, DSEK replaces only the damaged posterior layers, helping preserve more of the patient's healthy corneal tissue.
When Is DSEK/DSAEK Recommended?
An ophthalmologist may recommend DSEK surgery for conditions such as Fuchs' endothelial corneal dystrophy, corneal swelling, bullous keratopathy, or a previously failed corneal graft. The procedure may be considered when damaged endothelial cells are unable to maintain the cornea's normal clarity.
How Is the Procedure Performed?
During DSEK/DSAEK, the surgeon removes the unhealthy endothelial tissue and carefully places a thin layer of healthy donor corneal tissue inside the eye. An air or gas bubble is generally used to position the graft against the recipient cornea while it attaches.
Benefits and Recovery
Potential benefits of DSEK corneal transplant surgery include a smaller surgical incision, preservation of much of the patient's cornea, and generally faster visual recovery than traditional full-thickness keratoplasty. Vision can take time to improve, and recovery varies depending on the underlying condition and individual healing.
Patients may need prescribed eye drops and follow-up examinations after surgery. In some cases, additional treatment may be required if the donor graft becomes displaced or does not attach properly.

