Descemet Membrane Endothelial Keratoplasty (DMEK) is an advanced corneal transplant procedure used to treat conditions affecting the inner endothelial layer of the cornea. Unlike a full-thickness corneal transplant, DMEK replaces only the damaged Descemet membrane and endothelial cells with healthy donor tissue. This tissue-sparing approach may help suitable patients achieve clearer vision while preserving more of their natural cornea.
When Is DMEK Recommended?
DMEK may be considered for patients with corneal endothelial disorders such as Fuchs endothelial corneal dystrophy, corneal swelling, or endothelial cell damage following previous eye surgery or other conditions. Common symptoms can include blurred or cloudy vision, glare, difficulty seeing in the morning, and gradual loss of visual clarity.
What Happens During DMEK?
During the procedure, the ophthalmic surgeon carefully removes the unhealthy endothelial layer and places a very thin donor graft inside the cornea. An air or gas bubble is generally used to position and support the graft while it attaches to the patient's cornea. The procedure requires specialized surgical expertise and careful postoperative monitoring.
Recovery and Benefits
Vision may improve gradually as the transplanted endothelial cells begin restoring the cornea's ability to maintain its clarity. Recovery varies between individuals. Potential benefits of DMEK surgery include replacing diseased endothelial tissue, preserving healthy corneal layers, and potentially providing improved visual clarity in appropriately selected patients.
Your ophthalmologist will assess your corneal health, eye history, visual needs, and overall suitability before recommending DMEK.

