Paracetamol (Acetaminophen) Overdose Treatment
A paracetamol overdose, also known as acetaminophen poisoning, can cause serious liver injury and requires prompt medical assessment. It may occur after taking too much paracetamol at once or unintentionally combining multiple medicines that contain paracetamol.
Emergency Assessment and Treatment
Treatment begins with a careful assessment of the amount and timing of medication taken, symptoms, medical history, and relevant blood tests. Healthcare professionals may check paracetamol blood levels, liver function, kidney function, and other parameters to determine the risk of toxicity.
When clinically indicated, N-acetylcysteine (NAC) may be administered as an antidote. Early treatment can help reduce the risk of severe liver damage, while patients with significant poisoning may require close monitoring and specialist care.
What Patients Should Know
Symptoms of paracetamol overdose can initially be mild or absent, but serious complications may develop later. Nausea, vomiting, abdominal discomfort, sweating, or unusual tiredness can occur. Anyone who may have taken more than the recommended dose should seek urgent medical attention rather than waiting for symptoms.

